Compile Data Set for Download or QSAR
Found 309 of ki data for polymerid = 6145
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM92441(RXP470, 1 | RXP470, Compound 4)copy SMILEScopy InChI
Affinity DataKi:  0.190nM ΔG°:  -13.3kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using matrix metalloproteinases.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X27HVPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50265078((4S)-5-amino-4-((2S)-2-((2S)-3-((4-bromophenyl)(hy...)copy SMILEScopy InChI
Affinity DataKi:  0.190nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50592891(CHEMBL5191016)copy SMILES
Affinity DataKi:  0.190nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB281XPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM92441(RXP470, 1 | RXP470, Compound 4)copy SMILEScopy InChI
Affinity DataKi:  0.200nM ΔG°:  -13.2kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50265078((4S)-5-amino-4-((2S)-2-((2S)-3-((4-bromophenyl)(hy...)copy SMILEScopy InChI
Affinity DataKi:  0.240nMpH: 6.8Assay Description:Inhibition of human MMP12 catalytic domain (98 to 266) at pH 6.8 by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50265078((4S)-5-amino-4-((2S)-2-((2S)-3-((4-bromophenyl)(hy...)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Binding affinity to human MMP12 catalytic domain (98 to 266) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50505154(CHEMBL4581500)copy SMILEScopy InChI
Affinity DataKi:  0.260nMAssay Description:Inhibition of human MMP12More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2ZSKPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50426080(CHEMBL2316257)copy SMILEScopy InChI
Affinity DataKi:  0.280nMAssay Description:Inhibition of human MMP12More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50426080(CHEMBL2316257)copy SMILEScopy InChI
Affinity DataKi:  0.280nMAssay Description:Binding affinity to human MMP12 catalytic domain (98 to 266) by isothermal titration calorimetryMore data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120258(US8691753, 95 bis)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50505152(CHEMBL4435285)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of human MMP12More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2ZSKPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50555050(CHEMBL4764575)copy SMILES
Affinity DataKi:  1nMAssay Description:Inhibition of human recombinant MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC361PPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50434226(CHEMBL2385483)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of MMP12 (unknown origin)-mediated Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B859HTPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50505151(CHEMBL4520279)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Inhibition of human MMP12 by photoaffinity probe based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2ZSKPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120222(US8691753, 71)copy SMILEScopy InChI
Affinity DataKi:  1.05nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50555052(CHEMBL4751015)copy SMILES
Affinity DataKi:  1.10nMAssay Description:Inhibition of human recombinant MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC361PPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50555051(CHEMBL4739996)copy SMILES
Affinity DataKi:  1.20nMAssay Description:Inhibition of human recombinant MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate by spectrophotometryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PC361PPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120212(US8691753, 61 | US8691753, 72)copy SMILEScopy InChI
Affinity DataKi:  1.63nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120242(US8691753, 91)copy SMILEScopy InChI
Affinity DataKi:  1.84nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM92443(MMP Inhibitor, 3 | Thiophene derivative, compound ...)copy SMILEScopy InChI
Affinity DataKi:  1.90nM ΔG°:  -11.9kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM92443(MMP Inhibitor, 3 | Thiophene derivative, compound ...)copy SMILEScopy InChI
Affinity DataKi:  1.92nM ΔG°:  -11.9kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using matrix metalloproteinases.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X27HVPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120246(US8691753, 95 | US8691753, 96)copy SMILEScopy InChI
Affinity DataKi:  1.92nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50294120(2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide | ...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of MMP12 (unknown origin)-mediated Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorimetric assayMore data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50434222(CHEMBL2385487)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of MMP12 (unknown origin)-mediated Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B859HTPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120191(US8691753, 39)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120217(US8691753, 66)copy SMILEScopy InChI
Affinity DataKi:  2.20nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM92446(Inhibitor, 16)copy SMILEScopy InChI
Affinity DataKi:  2.5nM ΔG°:  -11.7kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120252(US8691753, 101)copy SMILEScopy InChI
Affinity DataKi:  2.56nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120243(US8691753, 92)copy SMILEScopy InChI
Affinity DataKi:  2.58nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120254(US8691753, 103)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM92449(Inhibitor, 19)copy SMILEScopy InChI
Affinity DataKi:  2.90nM ΔG°:  -11.6kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM92447(Inhibitor, 17)copy SMILEScopy InChI
Affinity DataKi:  3.30nM ΔG°:  -11.6kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120215(US8691753, 64)copy SMILEScopy InChI
Affinity DataKi:  3.30nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM92448(Inhibitor, 18)copy SMILEScopy InChI
Affinity DataKi:  3.30nM ΔG°:  -11.6kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120168(US8691753, 16)copy SMILEScopy InChI
Affinity DataKi:  3.40nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120219(US8691753, 68)copy SMILEScopy InChI
Affinity DataKi:  3.5nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  3.60nM ΔG°:  -11.5kcal/molepH: 6.8 T: 2°CAssay Description:Enzyme assay using human matrix metalloproteases or ADAMTS.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H993SBPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM92445(Inhibitor, 10 | US8691753, 105)copy SMILEScopy InChI
Affinity DataKi:  3.65nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM92443(MMP Inhibitor, 3 | Thiophene derivative, compound ...)copy SMILEScopy InChI
Affinity DataKi:  3.70nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120256(US8691753, 106)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120221(US8691753, 70)copy SMILEScopy InChI
Affinity DataKi:  4.70nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50433864(CHEMBL2380403)copy SMILEScopy InChI
Affinity DataKi:  4.80nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50434224(CHEMBL2385485)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of MMP12 (unknown origin)-mediated Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B859HTPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50592895(CHEMBL5187653)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB281XPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50434213(CHEMBL2385489)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Inhibition of MMP12 (unknown origin)-mediated Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B859HTPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120213(US8691753, 62)copy SMILEScopy InChI
Affinity DataKi:  5.20nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120173(US8691753, 21)copy SMILEScopy InChI
Affinity DataKi:  5.40nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM120250(US8691753, 99)copy SMILEScopy InChI
Affinity DataKi:  5.40nMAssay Description:The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28P5Z5QUS Patent
TargetMacrophage metalloelastase(Homo sapiens (Human))
Commissariat à l'Energie Atomique

LigandPNGBDBM50332949((R)-N,3-dihydroxy-2-(4-methoxyphenylsulfonamido)pr...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of MMP12 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5N2WPubMedMMDB
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